Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Co-expression
Experiments
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[Homology]
Score
hps1Hermansky-Pudlak syndrome 1 protein isoform X1. (673 aa)    
Predicted Functional Partners:
hps4
Hermansky-Pudlak syndrome 4 protein isoform X1.
     
 0.922
hps6
Hermansky-Pudlak syndrome 6 protein.
     
 0.855
hps3
Hermansky-Pudlak syndrome 3 protein isoform X1.
      
 0.777
LOC108272579
Dysbindin-like isoform X1.
     
 0.695
bloc1s6
Biogenesis of lysosome-related organelles complex 1 subunit 6; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. May play a role in intracellular vesicle trafficking, particular [...]
     
 0.637
tepsin
AP-4 complex accessory subunit tepsin isoform X2.
      
 0.629
gtf2h1
General transcription factor IIH subunit 1.
      
 0.628
arglu1
Arginine and glutamate-rich protein 1.
      
 0.615
bloc1s3
Biogenesis of lysosome-related organelles complex 1 subunit 3.
     
 0.610
hpdl
4-hydroxyphenylpyruvate dioxygenase.
     
 0.606
Your Current Organism:
Ictalurus punctatus
NCBI taxonomy Id: 7998
Other names: I. punctatus, Silurus punctatus, channel catfish
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