Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
vdrVitamin D3 receptor. (428 aa)    
Predicted Functional Partners:
fgf23
Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family.
   
 
 0.827
ENSIPUP00000018941
annotation not available
      
 0.793
ENSIPUP00000016033
GC vitamin D binding protein.
   
 
 0.780
ncor2
Nuclear receptor corepressor 2 isoform X2.
    
 0.762
ncor1
Nuclear receptor corepressor 1 isoform X16.
    
 0.762
med1
Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
    
 0.695
LOC108271345
Vitamin D 25-hydroxylase; Belongs to the cytochrome P450 family.
   
 0.690
LOC108278312
Retinoic acid receptor RXR-gamma-A-like isoform X1.
   
 0.686
LOC108267229
Retinoic acid receptor RXR-beta-B-like.
   
 0.686
LOC108272672
Retinoic acid receptor RXR-beta-A isoform X3.
   
 0.686
Your Current Organism:
Ictalurus punctatus
NCBI taxonomy Id: 7998
Other names: I. punctatus, Silurus punctatus, channel catfish
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