Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
adarb2Double-stranded RNA-specific editase B2. (708 aa)    
Predicted Functional Partners:
Pura
Transcriptional activator protein Pur-alpha.
      
 0.919
hnrnpa3
Heterogeneous nuclear ribonucleoprotein A3 2.
   
 
 0.760
alyref
THO complex subunit 4 isoform X2.
      
 0.743
eif2ak2
Interferon-induced, double-stranded RNA-activated protein kinase isoform X2.
   
 0.673
c9orf72
Protein C9orf72 homolog.
      
 0.594
LOC108268831
Transcriptional activator protein Pur-alpha-like.
      
 0.564
prkra
Interferon-inducible double-stranded RNA-dependent protein kinase activator A isoform X1.
    
 0.543
tarbp2
RISC-loading complex subunit TARBP2; Required for formation of the RNA induced silencing complex (RISC). Component of the RISC loading complex (RLC), also known as the micro-RNA (miRNA) loading complex (miRLC), which is composed of DICER1, AGO2 and TARBP2. Within the RLC/miRLC, DICER1 and TARBP2 are required to process precursor miRNAs (pre-miRNAs) to mature miRNAs and then load them onto AGO2. AGO2 bound to the mature miRNA constitutes the minimal RISC and may subsequently dissociate from DICER1 and TARBP2. May also play a role in the production of short interfering RNAs (siRNAs) from [...]
    
 0.543
nkrf
NF-kappa-B-repressing factor isoform X2.
    
   0.519
LOC108278348
MDS1 and EVI1 complex locus protein EVI1-like isoform X1.
      
 0.518
Your Current Organism:
Ictalurus punctatus
NCBI taxonomy Id: 7998
Other names: I. punctatus, Silurus punctatus, channel catfish
Server load: medium (48%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.