Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
LOC108272199Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1161 aa)    
Predicted Functional Partners:
gnas
Guanine nucleotide-binding protein G(S) subunit alpha.
   
 0.956
nudt2
Bis(5'-nucleosyl)-tetraphosphatase [asymmetrical].
     
  0.900
ntpcr
Cancer-related nucleoside-triphosphatase.
     
  0.900
prkacb
cAMP-dependent protein kinase catalytic subunit beta isoform X1; Belongs to the protein kinase superfamily.
    
 0.874
kapca
Camp-dependent protein kinase catalytic subunit alpha isoform X1; Belongs to the protein kinase superfamily.
    
 0.874
prkaca
cAMP-dependent protein kinase catalytic subunit alpha; Belongs to the protein kinase superfamily.
    
 0.874
LOC108267323
cAMP-dependent protein kinase catalytic subunit beta isoform X2; Belongs to the protein kinase superfamily.
    
 0.874
LOC108262790
Guanine nucleotide-binding protein G(Olf) subunit alpha-like.
   
 0.847
gnal
Guanine Nucleotide-binding protein G(olf) subunit alpha.
   
 0.847
LOC108263758
Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
    
 0.828
Your Current Organism:
Ictalurus punctatus
NCBI taxonomy Id: 7998
Other names: I. punctatus, Silurus punctatus, channel catfish
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