Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
dclre1b5' exonuclease Apollo. (588 aa)    
Predicted Functional Partners:
terf2ip
Telomeric repeat-binding factor 2-interacting protein 1 isoform X1.
    
 
 0.982
terf1
Telomeric repeat-binding factor; Binds the telomeric double-stranded 5'-TTAGGG-3' repeat.
   
 
 0.918
LOC108267930
Uncharacterized protein LOC108267930 isoform X1.
   
 
 0.899
pot1
Protection of telomeres protein 1 isoform X1.
   
 
 0.879
fan1
Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family.
    
 0.838
xrcc5
X-ray repair cross-complementing protein 5; Single-stranded DNA-dependent ATP-dependent helicase. Belongs to the ku80 family.
    
 0.838
poll
DNA polymerase lambda; Belongs to the DNA polymerase type-X family.
  
 
 0.831
mus81
Crossover junction endonuclease MUS81.
   
 0.823
fancm
Fanconi anemia group M protein.
   
 0.822
fancd2
Fanconi anemia group D2 protein isoform X2.
   
 0.812
Your Current Organism:
Ictalurus punctatus
NCBI taxonomy Id: 7998
Other names: I. punctatus, Silurus punctatus, channel catfish
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