LOC108273944 protein (Ictalurus punctatus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Ictalurus punctatus

NCBI taxonomy Id: 7998
Other names: I. punctatus, Silurus punctatus, channel catfish

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC108259383	LOC108265410	ENSIPUP00000016935	ENSIPUP00000005324	CREB-binding protein-like isoform X3.	Transcription factor 7-like 1-B.	0.970
LOC108259383	LOC108267915	ENSIPUP00000016935	ENSIPUP00000028967	CREB-binding protein-like isoform X3.	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	0.989
LOC108259383	LOC108273944	ENSIPUP00000016935	ENSIPUP00000001195	CREB-binding protein-like isoform X3.	Histone acetyltransferase p300-like isoform X6.	0.985
LOC108259383	lef1	ENSIPUP00000016935	ENSIPUP00000013133	CREB-binding protein-like isoform X3.	Lymphoid enhancer-binding factor 1 isoform X1.	0.973
LOC108259383	maml1	ENSIPUP00000016935	ENSIPUP00000018722	CREB-binding protein-like isoform X3.	Mastermind-like protein 1 isoform X1.	0.962
LOC108259383	sp1	ENSIPUP00000016935	ENSIPUP00000036790	CREB-binding protein-like isoform X3.	Transcription factor Sp1.	0.987
LOC108259383	tcf7	ENSIPUP00000016935	ENSIPUP00000030727	CREB-binding protein-like isoform X3.	Transcription factor 7 isoform X6.	0.964
LOC108259383	tcf7l2	ENSIPUP00000016935	ENSIPUP00000024052	CREB-binding protein-like isoform X3.	Transcription factor 7-like 2 isoform X2.	0.970
LOC108259383	tp53	ENSIPUP00000016935	ENSIPUP00000031919	CREB-binding protein-like isoform X3.	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression (By similarity); Belongs to the p53 family.	0.989
LOC108265410	LOC108259383	ENSIPUP00000005324	ENSIPUP00000016935	Transcription factor 7-like 1-B.	CREB-binding protein-like isoform X3.	0.970
LOC108265410	LOC108273944	ENSIPUP00000005324	ENSIPUP00000001195	Transcription factor 7-like 1-B.	Histone acetyltransferase p300-like isoform X6.	0.972
LOC108265410	LOC108279275	ENSIPUP00000005324	ENSIPUP00000018515	Transcription factor 7-like 1-B.	CREB-binding protein-like isoform X2.	0.970
LOC108265410	lef1	ENSIPUP00000005324	ENSIPUP00000013133	Transcription factor 7-like 1-B.	Lymphoid enhancer-binding factor 1 isoform X1.	0.925
LOC108265410	tcf7	ENSIPUP00000005324	ENSIPUP00000030727	Transcription factor 7-like 1-B.	Transcription factor 7 isoform X6.	0.709
LOC108265410	tcf7l2	ENSIPUP00000005324	ENSIPUP00000024052	Transcription factor 7-like 1-B.	Transcription factor 7-like 2 isoform X2.	0.540
LOC108267915	LOC108259383	ENSIPUP00000028967	ENSIPUP00000016935	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	CREB-binding protein-like isoform X3.	0.989
LOC108267915	LOC108273944	ENSIPUP00000028967	ENSIPUP00000001195	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	Histone acetyltransferase p300-like isoform X6.	0.991
LOC108267915	LOC108279275	ENSIPUP00000028967	ENSIPUP00000018515	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	CREB-binding protein-like isoform X2.	0.989
LOC108267915	sp1	ENSIPUP00000028967	ENSIPUP00000036790	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	Transcription factor Sp1.	0.917
LOC108267915	tp53	ENSIPUP00000028967	ENSIPUP00000031919	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression (By similarity); Belongs to the p53 family.	0.903