STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
LOC108271583Guanine nucleotide-binding protein G(T) subunit alpha-1. (350 aa)    
Predicted Functional Partners:
LOC108257427
Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
   
 0.990
LOC108272010
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1-like.
   
 0.982
LOC108265728
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1.
   
 0.982
LOC108280996
Rhodopsin.
   
 0.976
RHO
Rhodopsin.
   
 0.976
rho
Rhodopsin; Photoreceptor required for image-forming vision at low light intensity. While most salt water fish species use retinal as chromophore, most freshwater fish use 3-dehydroretinal, or a mixture of retinal and 3-dehydroretinal (By similarity). Light-induced isomerization of 11-cis to all-trans retinal triggers a conformational change that activates signaling via G-proteins. Subsequent receptor phosphorylation mediates displacement of the bound G-protein alpha subunit by arrestin and terminates signaling (By similarity).
   
 0.976
pde6g
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma.
   
 0.964
LOC108273767
Regulator of G-protein signaling 9-like isoform X2.
   
 0.963
LOC108278703
Regulator of G-protein signaling 9-like isoform X1.
   
 0.963
pde6a
Phosphodiesterase.
   
 0.940
Your Current Organism:
Ictalurus punctatus
NCBI taxonomy Id: 7998
Other names: I. punctatus, Silurus punctatus, channel catfish
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