Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
hsd11b1lHydroxysteroid 11-beta-dehydrogenase 1-like protein. (288 aa)    
Predicted Functional Partners:
cyp17
Steroid 17-alpha-hydroxylase/17,20 lyase; Conversion of pregnenolone and progesterone to their 17- alpha-hydroxylated products and subsequently to dehydroepiandrosterone (DHEA) and androstenedione. Catalyzes both the 17-alpha-hydroxylation and the 17,20-lyase reaction.
   
 
 0.938
hsd17b7
3-keto-steroid reductase.
     
 0.936
hsd17b12
Very-long-chain 3-oxoacyl-CoA reductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
   
0.933
dh12b
Estradiol 17-beta-dehydrogenase 12-B; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
   
0.933
LOC108275468
Steroid 17-alpha-hydroxylase/17,20 lyase-like isoform X1; Belongs to the cytochrome P450 family.
   
 
 0.928
LOC108261472
Steroid 21-hydroxylase-like; Belongs to the cytochrome P450 family.
   
 
 0.922
hsd17b1
Estradiol 17-beta-dehydrogenase 1 isoform X1; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
  
  
 0.921
hsd11b2
Corticosteroid 11-beta-dehydrogenase isozyme 2; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
   
 
0.920
LOC108275401
Estradiol 17-beta-dehydrogenase 2-like isoform X1; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
  
 
 
0.918
akr1d1
3-oxo-5-beta-steroid 4-dehydrogenase isoform X1.
  
 0.908
Your Current Organism:
Ictalurus punctatus
NCBI taxonomy Id: 7998
Other names: I. punctatus, Silurus punctatus, channel catfish
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