Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
LOC108272495D-beta-hydroxybutyrate dehydrogenase, mitochondrial-like; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (362 aa)    
Predicted Functional Partners:
oxct1
Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.
     
 0.981
hmgcl
hydroxymethylglutaryl-CoA lyase, mitochondrial isoform X1.
     
 0.963
LOC108255395
acetoacetyl-CoA synthetase.
     
 0.921
bdh2
3-hydroxybutyrate dehydrogenase type 2 isoform X1.
   
 
 0.624
acadm
Medium-chain specific Acyl-CoA dehydrogenase, mitochondrial.
   
 
 0.616
eci1
enoyl-CoA delta isomerase 1, mitochondrial; Belongs to the enoyl-CoA hydratase/isomerase family.
     
 0.581
dhtkd1
Probable 2-oxoglutarate dehydrogenase E1 component DHKTD1, mitochondrial.
   
 
 0.574
hadh
Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial.
   
 
 0.564
wdr53
WD repeat-containing protein 53.
      
 0.556
idh3a
Isocitrate dehydrogenase [NAD] subunit, mitochondrial.
    
 0.543
Your Current Organism:
Ictalurus punctatus
NCBI taxonomy Id: 7998
Other names: I. punctatus, Silurus punctatus, channel catfish
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