edem1 protein (Ictalurus punctatus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

edem1

alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (626 aa)

Predicted Functional Partners:

sel1l

0.986

canx

0.909

xbp1

0.891

dnajc10

0.884

derl2

0.841

LOC108268919

0.815

clgn

0.798

hsp90b1

0.777

dnajc3

0.770

hspa5

0.764

Your Current Organism:

Ictalurus punctatus

NCBI taxonomy Id: 7998
Other names: I. punctatus, Silurus punctatus, channel catfish

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC108268919	canx	ENSIPUP00000021951	ENSIPUP00000018908	Calnexin-like isoform X1.	Calnexin precursor.	0.902
LOC108268919	derl2	ENSIPUP00000021951	ENSIPUP00000034056	Calnexin-like isoform X1.	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	0.404
LOC108268919	dnajc10	ENSIPUP00000021951	ENSIPUP00000015714	Calnexin-like isoform X1.	dnaJ homolog subfamily C member 10 isoform X1.	0.714
LOC108268919	edem1	ENSIPUP00000021951	ENSIPUP00000001280	Calnexin-like isoform X1.	alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family.	0.815
LOC108268919	hsp90b1	ENSIPUP00000021951	ENSIPUP00000028141	Calnexin-like isoform X1.	Endoplasmin.	0.885
LOC108268919	hspa5	ENSIPUP00000021951	ENSIPUP00000029142	Calnexin-like isoform X1.	78 kDa glucose-regulated protein; Belongs to the heat shock protein 70 family.	0.930
LOC108268919	xbp1	ENSIPUP00000021951	ENSIPUP00000026920	Calnexin-like isoform X1.	LOW QUALITY PROTEIN: X-box-binding protein 1.	0.463
canx	LOC108268919	ENSIPUP00000018908	ENSIPUP00000021951	Calnexin precursor.	Calnexin-like isoform X1.	0.902
canx	derl2	ENSIPUP00000018908	ENSIPUP00000034056	Calnexin precursor.	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	0.417
canx	dnajc10	ENSIPUP00000018908	ENSIPUP00000015714	Calnexin precursor.	dnaJ homolog subfamily C member 10 isoform X1.	0.714
canx	edem1	ENSIPUP00000018908	ENSIPUP00000001280	Calnexin precursor.	alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family.	0.909
canx	hsp90b1	ENSIPUP00000018908	ENSIPUP00000028141	Calnexin precursor.	Endoplasmin.	0.934
canx	hspa5	ENSIPUP00000018908	ENSIPUP00000029142	Calnexin precursor.	78 kDa glucose-regulated protein; Belongs to the heat shock protein 70 family.	0.941
canx	sel1l	ENSIPUP00000018908	ENSIPUP00000027161	Calnexin precursor.	Protein sel-1 homolog 1 isoform X1.	0.411
canx	xbp1	ENSIPUP00000018908	ENSIPUP00000026920	Calnexin precursor.	LOW QUALITY PROTEIN: X-box-binding protein 1.	0.625
clgn	derl2	ENSIPUP00000014017	ENSIPUP00000034056	Calmegin isoform X2.	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	0.417
clgn	dnajc10	ENSIPUP00000014017	ENSIPUP00000015714	Calmegin isoform X2.	dnaJ homolog subfamily C member 10 isoform X1.	0.714
clgn	edem1	ENSIPUP00000014017	ENSIPUP00000001280	Calmegin isoform X2.	alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family.	0.798
clgn	hsp90b1	ENSIPUP00000014017	ENSIPUP00000028141	Calmegin isoform X2.	Endoplasmin.	0.904
clgn	hspa5	ENSIPUP00000014017	ENSIPUP00000029142	Calmegin isoform X2.	78 kDa glucose-regulated protein; Belongs to the heat shock protein 70 family.	0.941