Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
LOC10825479425-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial; Belongs to the cytochrome P450 family. (494 aa)    
Predicted Functional Partners:
LOC108271345
Vitamin D 25-hydroxylase; Belongs to the cytochrome P450 family.
  
0.956
LOC108271496
1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial; Belongs to the cytochrome P450 family.
  
  
0.911
vdr
Vitamin D3 receptor.
    
 0.682
LOC108271595
Transient receptor potential cation channel subfamily V member 6-like; Belongs to the transient receptor (TC 1.A.4) family.
    
 
 0.624
fdxr
NADPH:adrenodoxin oxidoreductase, mitochondrial.
     
 0.623
fgf23
Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family.
      
 0.614
med1
Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
    
  0.585
ro60
60 kDa SS-A/Ro ribonucleoprotein isoform X1.
      
 0.565
LOC108274321
Docosahexaenoic acid omega-hydroxylase CYP4F3-like.
  
 
 
 0.559
ENSIPUP00000021564
annotation not available
  
 
 
 0.533
Your Current Organism:
Ictalurus punctatus
NCBI taxonomy Id: 7998
Other names: I. punctatus, Silurus punctatus, channel catfish
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