Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
zic1Zinc finger protein ZIC 1. (454 aa)    
Predicted Functional Partners:
ryr3
Ryanodine receptor 3 isoform X3.
      
 0.760
tbr1
T-box brain protein 1.
    
 
 0.747
foxd3
Forkhead box protein D3.
   
 0.744
pomgnt2
Protein O-linked-mannose beta-1,4-N-acetylglucosaminyltransferase 2.
      
 0.701
enc1
Ectoderm-neural cortex protein 1.
    
 0.697
msx1
Homeobox protein MSX-1.
    
 0.696
svep1
Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 isoform X1.
    
 0.677
snx33
Sorting nexin.
      
 0.663
RYR3
Ryanodine receptor 3-like.
      
 0.662
rag1
V(D)J recombination-activating protein 1; Catalytic component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T-cell receptor genes in developing B and T- lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. In the RAG complex, RAG1 mediates the DNA-binding to the conserved recombination signal sequences (RSS) and catalyzes the DNA cleavage activities by introducing a double-strand break [...]
   
 
 0.634
Your Current Organism:
Ictalurus punctatus
NCBI taxonomy Id: 7998
Other names: I. punctatus, Silurus punctatus, channel catfish
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