Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
LOC108268462Homeobox protein EMX1-like. (232 aa)    
Predicted Functional Partners:
pax2
Paired box protein Pax-2 isoform X7.
    
 0.557
foxg1
Forkhead box protein G1.
   
 0.528
polb
DNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity.
    
   0.519
ctnnb1
Catenin beta-1 isoform X3.
     
 0.493
LOC108256067
Doublesex- and mab-3-related transcription factor 2-like.
   
 
 0.493
gata4
Transcription factor GATA-4.
     
 0.490
gata5
Transcription factor GATA-5 isoform X1.
     
 0.490
dnmt1
DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.
      
 0.488
LOC108279175
LIM/homeobox protein Lhx5.
    
 0.480
ift140
LOW QUALITY PROTEIN: intraflagellar transport protein 140 homolog.
      
 0.475
Your Current Organism:
Ictalurus punctatus
NCBI taxonomy Id: 7998
Other names: I. punctatus, Silurus punctatus, channel catfish
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