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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pcf11pre-mRNA cleavage complex 2 protein Pcf11. (1489 aa)    
Predicted Functional Partners:
clp1
Polyribonucleotide 5'-hydroxyl-kinase Clp1; Polynucleotide kinase that can phosphorylate the 5'-hydroxyl groups of double-stranded RNA (dsRNA), single-stranded RNA (ssRNA), double stranded DNA (dsDNA) and double-stranded DNA:RNA hybrids. dsRNA is phosphorylated more efficiently than dsDNA, and the RNA component of a DNA:RNA hybrid is phosphorylated more efficiently than the DNA component. Appears to have roles in both tRNA splicing and mRNA 3'-end formation. Component of the tRNA splicing endonuclease complex. Phosphorylates the 5'-terminus of the tRNA 3'-exon during tRNA splicing; thi [...]
    
 0.999
cstf3
Cleavage stimulation factor subunit 3.
    
 0.997
cpsf2
Cleavage and polyadenylation specificity factor subunit 2.
   
 0.994
cpsf1
Cleavage and polyadenylation specificity factor subunit 1 isoform X2.
    
 0.991
sympk
Symplekin.
    
 0.991
cpsf3
Cleavage and polyadenylation specificity factor subunit 3.
   
 0.990
cstf2
Cleavage stimulation factor subunit 2 isoform X1.
    
 0.983
LOC108260848
LOW QUALITY PROTEIN: pre-mRNA 3'-end-processing factor FIP1-like.
    
 0.973
polr2a
DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 0.960
cpsf4
Cleavage and polyadenylation specificity factor subunit 4.
   
 0.946
Your Current Organism:
Ictalurus punctatus
NCBI taxonomy Id: 7998
Other names: I. punctatus, Silurus punctatus, channel catfish
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