LOC108280372 protein (Ictalurus punctatus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

LOC108280372

Malic enzyme. (596 aa)

Predicted Functional Partners:

fh

0.979

LOC108267638

0.975

LOC108278882

0.975

mdh2

0.972

pdhb

0.967

ldha

0.958

LOC108275055

0.958

ldhb

0.958

LOC108258652

0.956

LOC108269785

0.956

Your Current Organism:

Ictalurus punctatus

NCBI taxonomy Id: 7998
Other names: I. punctatus, Silurus punctatus, channel catfish

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC108258652	LOC108267638	ENSIPUP00000008531	ENSIPUP00000002536	Malate dehydrogenase.	Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.	0.953
LOC108258652	LOC108269785	ENSIPUP00000008531	ENSIPUP00000019430	Malate dehydrogenase.	Malate dehydrogenase.	0.900
LOC108258652	LOC108275055	ENSIPUP00000008531	ENSIPUP00000034378	Malate dehydrogenase.	L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily.	0.750
LOC108258652	LOC108278882	ENSIPUP00000008531	ENSIPUP00000031081	Malate dehydrogenase.	Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.	0.953
LOC108258652	LOC108280372	ENSIPUP00000008531	ENSIPUP00000001451	Malate dehydrogenase.	Malic enzyme.	0.956
LOC108258652	fh	ENSIPUP00000008531	ENSIPUP00000006833	Malate dehydrogenase.	Fumarate hydratase, mitochondrial.	0.985
LOC108258652	ldha	ENSIPUP00000008531	ENSIPUP00000008642	Malate dehydrogenase.	L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily.	0.415
LOC108258652	ldhb	ENSIPUP00000008531	ENSIPUP00000036017	Malate dehydrogenase.	L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily.	0.732
LOC108258652	mdh2	ENSIPUP00000008531	ENSIPUP00000027200	Malate dehydrogenase.	Malate dehydrogenase.	0.980
LOC108258652	pdhb	ENSIPUP00000008531	ENSIPUP00000015164	Malate dehydrogenase.	Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.	0.708
LOC108267638	LOC108258652	ENSIPUP00000002536	ENSIPUP00000008531	Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.	Malate dehydrogenase.	0.953
LOC108267638	LOC108269785	ENSIPUP00000002536	ENSIPUP00000019430	Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.	Malate dehydrogenase.	0.953
LOC108267638	LOC108275055	ENSIPUP00000002536	ENSIPUP00000034378	Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.	L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily.	0.965
LOC108267638	LOC108278882	ENSIPUP00000002536	ENSIPUP00000031081	Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.	Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.	0.900
LOC108267638	LOC108280372	ENSIPUP00000002536	ENSIPUP00000001451	Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.	Malic enzyme.	0.975
LOC108267638	fh	ENSIPUP00000002536	ENSIPUP00000006833	Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.	Fumarate hydratase, mitochondrial.	0.558
LOC108267638	ldha	ENSIPUP00000002536	ENSIPUP00000008642	Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.	L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily.	0.952
LOC108267638	ldhb	ENSIPUP00000002536	ENSIPUP00000036017	Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.	L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily.	0.952
LOC108267638	mdh2	ENSIPUP00000002536	ENSIPUP00000027200	Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.	Malate dehydrogenase.	0.969
LOC108267638	pdhb	ENSIPUP00000002536	ENSIPUP00000015164	Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.	Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.	0.946