| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| LOC108272950 | ago2 | ENSIPUP00000033885 | ENSIPUP00000001454 | Trinucleotide repeat-containing gene 6C protein-like isoform X1. | Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include ago2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] | 0.878 |
| LOC108272950 | dgcr8 | ENSIPUP00000033885 | ENSIPUP00000024835 | Trinucleotide repeat-containing gene 6C protein-like isoform X1. | Microprocessor complex subunit DGCR8. | 0.407 |
| LOC108272950 | dicer1 | ENSIPUP00000033885 | ENSIPUP00000007458 | Trinucleotide repeat-containing gene 6C protein-like isoform X1. | Endoribonuclease Dicer isoform X2; Belongs to the helicase family. Dicer subfamily. | 0.536 |
| LOC108272950 | drosha | ENSIPUP00000033885 | ENSIPUP00000031611 | Trinucleotide repeat-containing gene 6C protein-like isoform X1. | Ribonuclease 3. | 0.476 |
| LOC108272950 | xpo5 | ENSIPUP00000033885 | ENSIPUP00000011534 | Trinucleotide repeat-containing gene 6C protein-like isoform X1. | Exportin-5. | 0.458 |
| ago2 | LOC108272950 | ENSIPUP00000001454 | ENSIPUP00000033885 | Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include ago2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] | Trinucleotide repeat-containing gene 6C protein-like isoform X1. | 0.878 |
| ago2 | dgcr8 | ENSIPUP00000001454 | ENSIPUP00000024835 | Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include ago2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] | Microprocessor complex subunit DGCR8. | 0.785 |
| ago2 | dicer1 | ENSIPUP00000001454 | ENSIPUP00000007458 | Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include ago2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] | Endoribonuclease Dicer isoform X2; Belongs to the helicase family. Dicer subfamily. | 0.930 |
| ago2 | drosha | ENSIPUP00000001454 | ENSIPUP00000031611 | Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include ago2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] | Ribonuclease 3. | 0.955 |
| ago2 | polr2a | ENSIPUP00000001454 | ENSIPUP00000003782 | Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include ago2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] | DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.774 |
| ago2 | prkra | ENSIPUP00000001454 | ENSIPUP00000028634 | Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include ago2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] | Interferon-inducible double-stranded RNA-dependent protein kinase activator A isoform X1. | 0.891 |
| ago2 | tarbp2 | ENSIPUP00000001454 | ENSIPUP00000035347 | Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include ago2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] | RISC-loading complex subunit TARBP2; Required for formation of the RNA induced silencing complex (RISC). Component of the RISC loading complex (RLC), also known as the micro-RNA (miRNA) loading complex (miRLC), which is composed of DICER1, AGO2 and TARBP2. Within the RLC/miRLC, DICER1 and TARBP2 are required to process precursor miRNAs (pre-miRNAs) to mature miRNAs and then load them onto AGO2. AGO2 bound to the mature miRNA constitutes the minimal RISC and may subsequently dissociate from DICER1 and TARBP2. May also play a role in the production of short interfering RNAs (siRNAs) from [...] | 0.891 |
| ago2 | tnrc6a | ENSIPUP00000001454 | ENSIPUP00000002205 | Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include ago2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] | Trinucleotide repeat-containing gene 6A protein. | 0.840 |
| ago2 | tnrc6c | ENSIPUP00000001454 | ENSIPUP00000001180 | Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include ago2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] | Trinucleotide repeat-containing gene 6C protein isoform X1. | 0.840 |
| ago2 | xpo5 | ENSIPUP00000001454 | ENSIPUP00000011534 | Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include ago2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] | Exportin-5. | 0.854 |
| dgcr8 | LOC108272950 | ENSIPUP00000024835 | ENSIPUP00000033885 | Microprocessor complex subunit DGCR8. | Trinucleotide repeat-containing gene 6C protein-like isoform X1. | 0.407 |
| dgcr8 | ago2 | ENSIPUP00000024835 | ENSIPUP00000001454 | Microprocessor complex subunit DGCR8. | Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include ago2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] | 0.785 |
| dgcr8 | dicer1 | ENSIPUP00000024835 | ENSIPUP00000007458 | Microprocessor complex subunit DGCR8. | Endoribonuclease Dicer isoform X2; Belongs to the helicase family. Dicer subfamily. | 0.985 |
| dgcr8 | drosha | ENSIPUP00000024835 | ENSIPUP00000031611 | Microprocessor complex subunit DGCR8. | Ribonuclease 3. | 0.999 |
| dgcr8 | prkra | ENSIPUP00000024835 | ENSIPUP00000028634 | Microprocessor complex subunit DGCR8. | Interferon-inducible double-stranded RNA-dependent protein kinase activator A isoform X1. | 0.815 |
