Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
mitfMicrophthalmia-associated transcription factor isoform X1. (413 aa)    
Predicted Functional Partners:
LOC108256206
Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.
    
 0.967
mapk1
Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.
    
 0.967
mpv17
Protein Mpv17 isoform X3; Belongs to the peroxisomal membrane protein PXMP2/4 family.
   
  
 0.934
dct
L-dopachrome tautomerase.
    
 0.923
LOC108276335
Microphthalmia-associated transcription factor-like isoform X2.
  
  
 
0.903
sox10
Transcription factor SOX-10.
    
 0.860
kit
Mast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
   
 0.831
LOC108260967
5,6-dihydroxyindole-2-carboxylic acid oxidase-like.
    
 0.828
sumo1
Small ubiquitin-related modifier.
    
 0.802
ENSIPUP00000010252
Melanocortin 1 receptor.
   
 
 0.794
Your Current Organism:
Ictalurus punctatus
NCBI taxonomy Id: 7998
Other names: I. punctatus, Silurus punctatus, channel catfish
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