Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ccdc105Coiled-coil domain-containing protein 105. (479 aa)    
Predicted Functional Partners:
fau
40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family.
   
 0.995
rpsa
40S ribosomal protein SA; Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA- precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. Also functions as a cell surface receptor for laminin. Plays a role in cell adhesion to the basement membrane and in the consequent activation of signaling transduction pathways. May play a role in cell fate determination and tissue morphogenesis. Belongs to the universal ribosomal protein uS2 family.
  
 0.984
efhb
EF-hand domain-containing family member B.
   
 
 0.975
rps18
40S ribosomal protein S18; Located at the top of the head of the 40S subunit, it contacts several helices of the 18S rRNA; Belongs to the universal ribosomal protein uS13 family.
  
 0.968
rps3
40S ribosomal protein S3; Involved in translation as a component of the 40S small ribosomal subunit. Has endonuclease activity and plays a role in repair of damaged DNA. Also involved in other processes including regulation of transcription, translation of its cognate mRNA, spindle formation and chromosome movement during mitosis, and apoptosis.
  
 0.968
rps20
40S ribosomal protein S20.
  
 0.968
rps16
40S ribosomal protein S16; Belongs to the universal ribosomal protein uS9 family.
  
 0.967
rps9
40S ribosomal protein S9 isoform X1; Belongs to the universal ribosomal protein uS4 family.
  
 0.966
rps3a
40S ribosomal protein S3a; Belongs to the eukaryotic ribosomal protein eS1 family.
   
 0.965
rps19
40S ribosomal protein S19; Belongs to the eukaryotic ribosomal protein eS19 family.
   
 0.964
Your Current Organism:
Ictalurus punctatus
NCBI taxonomy Id: 7998
Other names: I. punctatus, Silurus punctatus, channel catfish
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