Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
usp45Ubiquitin carboxyl-terminal hydrolase. (777 aa)    
Predicted Functional Partners:
usp16
Ubiquitin carboxyl-terminal hydrolase.
  
  
 
0.905
ercc1
DNA excision repair protein ERCC-1.
    
 0.839
otud6b
OTU domain-containing protein 6B.
      
 0.704
ice2
Little elongation complex subunit 2.
      
 0.693
klhl7
Kelch-like protein 7.
      
 0.674
mipol1
Mirror-image polydactyly gene 1 protein isoform X1.
      
 0.663
coq3
Ubiquinone biosynthesis O-methyltransferase, mitochondrial; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family.
      
 0.648
il10
Interleukin-10.
      
 0.628
mysm1
Histone H2A deubiquitinase MYSM1.
   
  
 0.597
pibf1
Progesterone-induced-blocking factor 1 isoform X1.
      
 0.581
Your Current Organism:
Ictalurus punctatus
NCBI taxonomy Id: 7998
Other names: I. punctatus, Silurus punctatus, channel catfish
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