Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
birc2Baculoviral IAP repeat-containing protein 2 isoform X1. (616 aa)    
Predicted Functional Partners:
tnfrsf1a
Tumor necrosis factor receptor superfamily member 1A.
    
 0.990
casp9
Caspase-9 isoform X2; Belongs to the peptidase C14A family.
   
 0.990
casp7
Caspase-7 isoform X1; Belongs to the peptidase C14A family.
   
 0.987
LOC108278350
Diablo homolog, mitochondrial-like.
    
 0.986
tradd
Tumor necrosis factor receptor type 1-associated DEATH domain protein isoform X2.
   
 0.985
xiap
E3 ubiquitin-protein ligase XIAP isoform X2.
   
 
0.981
LOC108269206
E3 ubiquitin-protein ligase XIAP-like isoform X1.
   
 
0.981
LOC108279085
Diablo homolog, mitochondrial-like.
    
 0.981
LOC108260860
Caspase-3-like; Belongs to the peptidase C14A family.
   
 0.978
ripk1
Receptor-interacting serine/threonine-protein kinase 1 isoform X1.
   
 0.977
Your Current Organism:
Ictalurus punctatus
NCBI taxonomy Id: 7998
Other names: I. punctatus, Silurus punctatus, channel catfish
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