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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
egln3Egl nine homolog 3 isoform X1. (306 aa)    
Predicted Functional Partners:
LOC100305068
Hypoxia induced factor 1 alpha.
    
 0.772
LOC100304653
Hypoxia induced factor-like factor.
    
 0.765
LOC108273968
Endothelial PAS domain-containing protein 1-like isoform X1.
    
 0.765
ENSIPUP00000011548
Endothelial PAS domain-containing protein 1-like.
    
 0.765
epas1
Endothelial PAS domain-containing protein 1 isoform X1.
    
 0.765
vhl
Von Hippel-Lindau disease tumor suppressor.
    
 0.728
LOC108279075
Hypoxia-inducible factor 1-alpha-like isoform X1.
    
 0.685
npas3
Neuronal PAS domain-containing protein 3 isoform X1.
    
 0.684
hif1a
Hypoxia-inducible factor 1-alpha.
    
 0.684
npas1
Neuronal PAS domain-containing protein 1 isoform X2.
    
 0.684
Your Current Organism:
Ictalurus punctatus
NCBI taxonomy Id: 7998
Other names: I. punctatus, Silurus punctatus, channel catfish
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