Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
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[Homology]
Score
rnf2E3 ubiquitin-protein ligase RING2. (336 aa)    
Predicted Functional Partners:
pcgf3
Polycomb group RING finger protein 3 isoform X1.
   
 0.995
bmi1
Polycomb complex protein BMI-1.
   
 0.994
cbx2
Chromobox protein homolog 2 isoform X1.
    
 0.993
LOC108280883
Polycomb complex protein BMI-1-B-like.
   
 0.991
pcgf1
Polycomb group RING finger protein 1 isoform X1.
   
 0.990
LOC108257787
Transcription factor E2F6-like isoform X2.
    
 0.987
LOC108269597
Polycomb group RING finger protein 5-A-like.
   
 0.985
pcgf5
Polycomb group RING finger protein 5-A.
   
 0.980
pcgf6
Polycomb group RING finger protein 6 isoform X1.
   
 0.980
l3mbtl2
Lethal(3)malignant brain tumor-like protein 2.
    
 0.976
Your Current Organism:
Ictalurus punctatus
NCBI taxonomy Id: 7998
Other names: I. punctatus, Silurus punctatus, channel catfish
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