Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
trpc1Short transient receptor potential channel 1 isoform X1; Belongs to the transient receptor (TC 1.A.4) family. (799 aa)    
Predicted Functional Partners:
stim1
Stromal interaction molecule 1 isoform X1.
    
 0.969
trpv4
Transient receptor potential cation channel subfamily V member 4 isoform X1; Belongs to the transient receptor (TC 1.A.4) family.
     
 0.932
stim2
Stromal interaction molecule 2 isoform X2.
    
 0.927
cav3
Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.
    
 
 0.915
LOC108277929
Stromal interaction molecule 1-like.
    
 0.913
LOC108260897
Stromal interaction molecule 2-like.
    
 0.897
LOC108261176
Short transient receptor potential channel 5-like; Belongs to the transient receptor (TC 1.A.4) family.
    
 0.796
trpc4
Short transient receptor potential channel 4; Belongs to the transient receptor (TC 1.A.4) family.
    
 0.796
LOC108277864
Short transient receptor potential channel 4-like isoform X1; Belongs to the transient receptor (TC 1.A.4) family.
    
 0.796
trpm7
Transient receptor potential cation channel subfamily M member 7 isoform X4.
    
 0.787
Your Current Organism:
Ictalurus punctatus
NCBI taxonomy Id: 7998
Other names: I. punctatus, Silurus punctatus, channel catfish
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