Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LOC108275733NACHT, LRR and PYD domains-containing protein 12-like isoform X2. (1189 aa)    
Predicted Functional Partners:
txnip
Thioredoxin-interacting protein.
    
 0.795
LOC108273074
Thioredoxin-interacting protein-like.
    
 0.795
brcc3
Lys-63-specific deubiquitinase BRCC36 isoform X1.
    
 0.722
nek7
Serine/threonine-protein kinase Nek7 isoform X2; Belongs to the protein kinase superfamily.
    
 
 0.645
LOC108267794
Caspase-4-like isoform X1; Belongs to the peptidase C14A family.
   
 0.612
prkn
Parkin RBR E3 ubiquitin protein ligase.
    
 
 0.573
ARRDC1
Arrestin domain-containing protein 1-like.
    
 0.472
arrdc1
Arrestin domain-containing protein 1.
    
 0.472
arrdc2
Arrestin domain-containing protein 2 isoform X2.
    
 0.472
LOC108255838
Arrestin domain-containing protein 3.
    
 0.472
Your Current Organism:
Ictalurus punctatus
NCBI taxonomy Id: 7998
Other names: I. punctatus, Silurus punctatus, channel catfish
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