Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
LOC108273913Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family. (781 aa)    
Predicted Functional Partners:
cs
Citrate synthase; Belongs to the citrate synthase family.
  
 0.999
idh3a
Isocitrate dehydrogenase [NAD] subunit, mitochondrial.
  
 0.999
idh2
Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family.
  
 0.996
LOC108268871
Malate synthase-like.
  
 0.996
mdh2
Malate dehydrogenase.
  
 0.996
idh1
Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family.
  
 0.996
atp5f1a
ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane.
  
 0.990
idh3b
Isocitrate dehydrogenase [NAD] subunit, mitochondrial.
  
 0.990
LOC108275983
Isocitrate dehydrogenase [NAD] subunit, mitochondrial.
  
 0.990
LOC108276129
Isocitrate dehydrogenase [NAD] subunit, mitochondrial.
  
 0.990
Your Current Organism:
Ictalurus punctatus
NCBI taxonomy Id: 7998
Other names: I. punctatus, Silurus punctatus, channel catfish
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