Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
mre11Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (698 aa)    
Predicted Functional Partners:
rbbp8
DNA endonuclease RBBP8.
   
 0.999
nbn
Nibrin.
   
 0.999
atm
Non-specific serine/threonine protein kinase.
   
 0.999
rad50
DNA repair protein RAD50 isoform X1.
  
 0.999
brca1
Breast cancer type 1 susceptibility protein isoform X2.
   
 0.995
bard1
BRCA1-associated RING domain protein 1.
   
 0.993
terf2ip
Telomeric repeat-binding factor 2-interacting protein 1 isoform X1.
    
 0.989
wrn
Werner syndrome ATP-dependent helicase isoform X1.
  
 0.983
blm
Bloom syndrome protein isoform X1.
  
 0.982
exo1
Exonuclease 1 isoform X1.
   
 0.982
Your Current Organism:
Ictalurus punctatus
NCBI taxonomy Id: 7998
Other names: I. punctatus, Silurus punctatus, channel catfish
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