Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
setd2Histone-lysine N-methyltransferase SETD2. (706 aa)    
Predicted Functional Partners:
iws1
Interacts with SUPT6H, CTD assembly factor 1.
   
 
 0.953
polr2a
DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 0.945
supt5h
Transcription elongation factor SPT5.
   
 
 0.943
supt6h
Transcription elongation factor spt6; Transcription elongation factor that enhances transcription elongation by RNA polymerase II (RNAPII). Belongs to the SPT6 family.
  
 
 0.942
htt
Huntingtin.
    
 
 0.941
supt16h
FACT complex subunit SPT16.
    
 
 0.936
polr2c
DNA-directed RNA polymerase II subunit RPB3 isoform X1.
   
 0.933
supt4h1
Transcription elongation factor SPT4; Component of the DRB sensitivity-inducing factor complex (DSIF complex), which regulates transcription elongation by RNA polymerase II; Belongs to the SPT4 family.
    
 
 0.924
ctr9
RNA polymerase-associated protein CTR9 homolog.
   
 0.915
cdc73
Parafibromin.
    
 
 0.909
Your Current Organism:
Ictalurus punctatus
NCBI taxonomy Id: 7998
Other names: I. punctatus, Silurus punctatus, channel catfish
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