Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
LOC108260713Melatonin receptor type 1A-A-like; Belongs to the G-protein coupled receptor 1 family. (346 aa)    
Predicted Functional Partners:
tenm1
Teneurin-1.
      
 0.683
fat2
Protocadherin Fat 2.
     
 0.614
aanat
Serotonin N-acetyltransferase.
      
 0.542
LOC108257103
Serotonin N-acetyltransferase-like.
      
 0.526
dlg2
Disks large homolog 2 isoform X2.
    
 0.488
LOC108271975
Disks large homolog 1-like isoform X5; Belongs to the MAGUK family.
    
 0.488
LOC108280564
Discs large homolog 1-like protein isoform X4; Belongs to the MAGUK family.
    
 0.488
trh
Pro-thyrotropin-releasing hormone; Functions as a regulator of the biosynthesis of TSH in the anterior pituitary gland and as a neurotransmitter/ neuromodulator in the central and peripheral nervous systems.
    
 0.488
fastk
Fas-activated Serine/threonine kinase.
      
 0.483
tectb
Beta-tectorin.
      
 0.480
Your Current Organism:
Ictalurus punctatus
NCBI taxonomy Id: 7998
Other names: I. punctatus, Silurus punctatus, channel catfish
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