Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
chtf18Chromosome transmission fidelity protein 18 homolog isoform X1. (952 aa)    
Predicted Functional Partners:
dscc1
Sister chromatid cohesion protein DCC1.
   
 0.999
rfc4
Replication factor C subunit 4 isoform X1.
   
 0.997
chtf8
Chromosome transmission fidelity protein 8-like protein.
   
 0.996
rfc5
Replication factor C subunit 5.
   
 0.995
pcna
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
   
 0.995
rfc3
Replication factor C subunit 3.
   
 0.992
rfc2
Replication factor C subunit 2.
   
 0.991
wdhd1
WD repeat and HMG-box DNA-binding protein 1 isoform X2.
   
 
 0.981
pola1
DNA polymerase.
   
 0.972
pole2
DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family.
   
 
 0.971
Your Current Organism:
Ictalurus punctatus
NCBI taxonomy Id: 7998
Other names: I. punctatus, Silurus punctatus, channel catfish
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