Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
engaseCytosolic endo-beta-N-acetylglucosaminidase isoform X2. (721 aa)    
Predicted Functional Partners:
ngly1
peptide-N(4)-(N-acetyl-beta- glucosaminyl)asparagine amidase isoform X1.
   
  
 0.913
rps27a
Ubiquitin-40S ribosomal protein S27a; Ubiquitin exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be invo [...]
     
  0.840
uba52
ubiquitin-60S ribosomal protein L40 isoform X1.
     
  0.820
man2c1
Alpha-mannosidase 2C1.
  
  
 0.779
LOC108255117
F-box only protein 2-like.
      
 0.615
LOC108276242
F-box only protein 6-like isoform X1.
      
 0.615
eipr1
Protein TSSC1.
      
 0.613
spata20
Spermatogenesis-associated protein 20 isoform X1.
      
 0.594
LOC108256747
Cysteine-rich venom protein pseudechetoxin-like; Belongs to the CRISP family.
      
 0.574
LOC108276559
CXADR-like membrane protein.
      
 0.555
Your Current Organism:
Ictalurus punctatus
NCBI taxonomy Id: 7998
Other names: I. punctatus, Silurus punctatus, channel catfish
Server load: low (12%) [HD]