Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
ern2Serine/threonine-protein kinase/endoribonuclease IRE2 isoform X1. (929 aa)    
Predicted Functional Partners:
xbp1
LOW QUALITY PROTEIN: X-box-binding protein 1.
    
 0.972
LOC108255825
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
   
 0.953
traf2
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
   
 0.953
map3k5
Mitogen-activated protein kinase kinase kinase 5.
    
0.949
hspa5
78 kDa glucose-regulated protein; Belongs to the heat shock protein 70 family.
    
 0.926
ern1
Serine/threonine-protein kinase/endoribonuclease IRE1.
  
  
 
0.902
sec63
Translocation protein SEC63 homolog.
    
 
 0.766
syvn1
E3 ubiquitin-protein ligase synoviolin.
    
 
 0.646
amfr
E3 ubiquitin-protein ligase AMFR.
    
 
 0.646
ube2g2
Ubiquitin-conjugating enzyme E2 G2; Belongs to the ubiquitin-conjugating enzyme family.
    
 
 0.622
Your Current Organism:
Ictalurus punctatus
NCBI taxonomy Id: 7998
Other names: I. punctatus, Silurus punctatus, channel catfish
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