Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
LOC108259679PHD finger protein 21A-like isoform X1. (847 aa)    
Predicted Functional Partners:
hmg20b
High mobility group 20B.
    
 0.983
kdm1a
Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family.
    
 0.977
hmg20a
High mobility group protein 20A isoform X1.
    
 0.957
rcor1
REST corepressor 1.
   
 0.854
rcor3
REST corepressor 3 isoform X1.
   
 0.843
rcor2
REST corepressor 2 isoform X3.
   
 0.843
hdac8
Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily.
   
 0.777
HDAC2
Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily.
   
 0.777
LOC108272688
Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily.
   
 0.777
arid4b
AT-rich interactive domain-containing protein 4B isoform X2.
    
 0.694
Your Current Organism:
Ictalurus punctatus
NCBI taxonomy Id: 7998
Other names: I. punctatus, Silurus punctatus, channel catfish
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