Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
prdm5Zinc finger protein. (630 aa)    
Predicted Functional Partners:
uros
uroporphyrinogen-III synthase isoform X2.
    
 
 0.821
pde6d
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta; Promotes the release of prenylated target proteins from cellular membranes. Modulates the activity of prenylated or palmitoylated Ras family members by regulating their subcellular location. Required for normal ciliary targeting of farnesylated target proteins, such as INPP5E. Modulates the subcellular location of target proteins by acting as a GTP specific dissociation inhibitor (GDI). Increases the affinity of ARL3 for GTP by several orders of magnitude. Stabilizes ARL3-GTP by decreasing the nucleotide [...]
    
 
 0.716
mlf1
Myeloid leukemia factor 1.
    
 
 0.608
fancm
Fanconi anemia group M protein.
    
  0.594
sh3rf3
SH3 domain-containing RING finger protein 3.
   
 0.520
oxsm
3-oxoacyl-[acyl-carrier-protein] synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
      
 0.519
fkbp14
Peptidylprolyl isomerase.
    
 0.515
LOC108256055
Hyaluronan and proteoglycan link protein 1-like.
    
 0.515
LOC108261073
Hyaluronan and proteoglycan link protein 1-like isoform X4.
    
 0.515
maats1
Protein MAATS1.
    
 0.515
Your Current Organism:
Ictalurus punctatus
NCBI taxonomy Id: 7998
Other names: I. punctatus, Silurus punctatus, channel catfish
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