Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
LOC108271291Dual specificity mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (412 aa)    
Predicted Functional Partners:
mapk1
Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.
   
0.986
lamtor3
Mitogen-activated protein kinase scaffold protein 1.
   
 0.982
LOC108256206
Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.
   
0.982
map3k8
Mitogen-activated protein kinase kinase kinase 8.
  
0.975
raf1
RAF proto-oncogene serine/threonine-protein kinase isoform X2.
   
0.971
braf
Serine/threonine-protein kinase B-raf.
   
0.971
LOC108276324
RAF proto-oncogene serine/threonine-protein kinase-like.
   
0.971
LOC108255753
Serine/threonine-protein kinase A-Raf-like isoform X3.
   
0.971
map3k1
Mitogen-activated protein kinase kinase kinase 1 isoform X1.
    
0.969
map2k1
Dual specificity mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily.
  
  
 
0.964
Your Current Organism:
Ictalurus punctatus
NCBI taxonomy Id: 7998
Other names: I. punctatus, Silurus punctatus, channel catfish
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