Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
snx6Sorting nexin; Involved in several stages of intracellular trafficking. (407 aa)    
Predicted Functional Partners:
snx2
Sorting nexin-2 isoform X1.
   
 0.992
LOC108274727
Sorting nexin-1-like isoform X1.
   
 0.955
vps29
Vacuolar protein sorting-associated protein 29; Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway.
    
 
 0.919
LOC108271812
Sorting nexin-6-like isoform X1.
     
 
0.900
vps26a
Vacuolar protein sorting-associated protein 26A.
   
 
 0.891
snx4
Sorting nexin-4.
   
 0.887
vps35
Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting.
   
 
 0.858
igf2r
Cation-independent mannose-6-phosphate receptor isoform X2.
    
 0.848
tbc1d5
TBC1 domain family member 5 isoform X1.
    
 
 0.830
snx27
Sorting nexin-27 isoform X1.
    
 
 0.825
Your Current Organism:
Ictalurus punctatus
NCBI taxonomy Id: 7998
Other names: I. punctatus, Silurus punctatus, channel catfish
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