Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
zbtb10Zinc finger and BTB domain-containing protein 10. (571 aa)    
Predicted Functional Partners:
rag1
V(D)J recombination-activating protein 1; Catalytic component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T-cell receptor genes in developing B and T- lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. In the RAG complex, RAG1 mediates the DNA-binding to the conserved recombination signal sequences (RSS) and catalyzes the DNA cleavage activities by introducing a double-strand break [...]
   
 
 0.613
huwe1
E3 ubiquitin-protein ligase HUWE1 isoform X9.
    
 0.563
dclre1b
5' exonuclease Apollo.
    
 
 0.511
naif1
Nuclear apoptosis-inducing factor 1 isoform X1.
      
 0.485
terf2
Telomeric repeat-binding factor 2 isoform X1.
    
 0.435
mysm1
Histone H2A deubiquitinase MYSM1.
   
  0.434
LOC108266093
Thioredoxin domain-containing protein 3 homolog; Belongs to the NDK family.
    
 0.428
srbd1
S1 RNA-binding domain-containing protein 1.
    
 
 0.414
nr2c1
Nuclear receptor subfamily 2 group C member 1.
    
 0.413
LOC108266078
poly(RC)-binding protein 3 isoform X3.
    
 0.406
Your Current Organism:
Ictalurus punctatus
NCBI taxonomy Id: 7998
Other names: I. punctatus, Silurus punctatus, channel catfish
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