Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
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[Homology]
Score
LOC108262495Histone H3; Belongs to the histone H3 family. (136 aa)    
Predicted Functional Partners:
kdm6b
Lysine-specific demethylase 6B.
   
 0.763
LOC108272609
Histone demethylase UTY-like isoform X1.
   
 0.763
LOC108277160
Lysine-specific demethylase 6B-like isoform X2.
   
 0.763
kdm6a
Lysine-specific demethylase 6A isoform X1.
   
 0.763
rbbp4
Histone-binding protein RBBP4.
   
 0.733
ezh2
Histone-lysine N-methyltransferase EZH2 isoform X1.
   
 0.730
mphosph8
M-phase phosphoprotein 8 isoform X1.
   
 0.725
arid4a
AT-rich interactive domain-containing protein 4A.
   
 0.711
arid4b
AT-rich interactive domain-containing protein 4B isoform X2.
   
 0.711
setd2
Histone-lysine N-methyltransferase SETD2.
    
 0.708
Your Current Organism:
Ictalurus punctatus
NCBI taxonomy Id: 7998
Other names: I. punctatus, Silurus punctatus, channel catfish
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