Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
gakcyclin-G-associated kinase isoform X2. (1287 aa)    
Predicted Functional Partners:
clhc1
Clathrin heavy chain linker domain-containing protein 1 isoform X1.
   
 0.993
cltc
Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.
   
 0.993
cltb
Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family.
    
 0.989
clta
Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family.
    
 0.989
dnajc6
Putative tyrosine-protein phosphatase auxilin isoform X1.
   
 0.985
hip1
Huntingtin-interacting protein 1 isoform X1.
   
 0.975
HIP1R
Huntingtin interacting protein 1 related.
   
 0.975
LOC108255864
Huntingtin-interacting protein 1-related protein-like isoform X1.
   
 0.975
LOC108279100
Clathrin interactor 1-like isoform X1.
    
 0.949
clint1
Clathrin interactor 1 isoform X2.
    
 0.949
Your Current Organism:
Ictalurus punctatus
NCBI taxonomy Id: 7998
Other names: I. punctatus, Silurus punctatus, channel catfish
Server load: medium (62%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.