Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
cfl2Cofilin-2; Belongs to the actin-binding proteins ADF family. (166 aa)    
Predicted Functional Partners:
limk2
LIM domain kinase 2 isoform X2.
   
 0.991
limk1
LIM domain kinase 1 isoform X1.
   
 0.991
LOC108278922
LIM domain kinase 1-like.
   
 0.981
LOC108268974
Protein phosphatase Slingshot homolog 3-like isoform X1.
    
 0.964
LOC108278835
Protein phosphatase Slingshot homolog 2-like isoform X1.
    
 0.964
LOC108277939
Protein phosphatase Slingshot homolog 2-like isoform X1.
    
 0.964
ssh1
Protein phosphatase Slingshot homolog 1 isoform X1.
    
 0.964
LOC108258691
Actin, cytoplasmic 1.
   
 0.952
actb
Actin, cytoplasmic 1.
   
 0.952
LOC108261049
Cofilin-2-like; Belongs to the actin-binding proteins ADF family.
  
  
 
0.903
Your Current Organism:
Ictalurus punctatus
NCBI taxonomy Id: 7998
Other names: I. punctatus, Silurus punctatus, channel catfish
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