Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
LOC108280976E3 ubiquitin-protein ligase DTX3L-like. (328 aa)    
Predicted Functional Partners:
LOC108266413
Poly [ADP-ribose] polymerase.
   
 0.837
LOC108277141
Poly [ADP-ribose] polymerase.
   
 0.823
LOC108266415
Poly [ADP-ribose] polymerase.
   
 0.760
f162b
UPF0389 protein FAM162B.
   
 0.760
LOC108276774
Poly [ADP-ribose] polymerase.
   
 0.760
nudcd1
nudC domain-containing protein 1.
    
   0.615
ddx58
Probable ATP-dependent RNA helicase DDX58.
   
 0.579
ifih1
Interferon-induced helicase C domain-containing protein 1.
   
 0.536
mib2
E3 ubiquitin-protein ligase MIB2 isoform X1.
    
 0.487
LOC108265473
Ubiquitin-conjugating enzyme E2 D4 isoform X1; Belongs to the ubiquitin-conjugating enzyme family.
    
 0.411
Your Current Organism:
Ictalurus punctatus
NCBI taxonomy Id: 7998
Other names: I. punctatus, Silurus punctatus, channel catfish
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