Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
LOC108276272Protein sel-1 homolog 3-like. (1124 aa)    
Predicted Functional Partners:
derl1
Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.
   
 0.914
derl2
Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.
   
 0.912
syvn1
E3 ubiquitin-protein ligase synoviolin.
   
 0.850
erlec1
Endoplasmic reticulum lectin 1 isoform X1.
   
 0.850
os9
Protein OS-9.
   
 0.850
amfr
E3 ubiquitin-protein ligase AMFR.
   
 0.850
spata5
Spermatogenesis-associated protein 5.
   
 0.769
vcp
Transitional Endoplasmic reticulum ATPase; Belongs to the AAA ATPase family.
   
 0.769
spata5l1
Spermatogenesis-associated protein 5-like protein 1.
   
 0.769
pltp
Phospholipid transfer protein.
    
   0.765
Your Current Organism:
Ictalurus punctatus
NCBI taxonomy Id: 7998
Other names: I. punctatus, Silurus punctatus, channel catfish
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