Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Co-occurrence
Co-expression
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[Homology]
Score
esco1N-acetyltransferase ESCO1. (978 aa)    
Predicted Functional Partners:
smc3
Structural maintenance of chromosomes protein.
   
 0.953
esco2
N-acetyltransferase ESCO2 isoform X1.
  
  
0.909
pcna
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
   
 0.885
pds5a
Sister chromatid cohesion protein PDS5 homolog A isoform X1.
   
 0.876
pds5b
Sister chromatid cohesion protein PDS5 homolog B.
   
 0.876
chtf18
Chromosome transmission fidelity protein 18 homolog isoform X1.
   
 
 0.856
ddx11
Probable ATP-dependent DNA helicase DDX11 isoform X1.
   
 
 0.848
LOC108256659
Double-strand-break repair protein rad21 homolog.
   
 0.844
LOC108265116
Double-strand-break repair protein rad21 homolog isoform X2.
   
 0.844
rad21
Double-strand-break repair protein rad21 homolog isoform X1.
   
 0.844
Your Current Organism:
Ictalurus punctatus
NCBI taxonomy Id: 7998
Other names: I. punctatus, Silurus punctatus, channel catfish
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