Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
hacd2Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] (246 aa)    
Predicted Functional Partners:
hsd17b12
Very-long-chain 3-oxoacyl-CoA reductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
   
 0.961
dh12b
Estradiol 17-beta-dehydrogenase 12-B; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
   
 0.961
LOC108255190
Very-long-chain enoyl-CoA reductase-like isoform X3.
   
 0.904
LOC108256782
Very-long-chain enoyl-CoA reductase-like.
   
 0.904
tecr
Very-long-chain enoyl-CoA reductase.
   
 0.904
LOC108280320
Very-long-chain enoyl-CoA reductase-like.
   
 0.904
LOC108269901
Exportin-1.
    
 
 0.735
LOC108258411
Exportin-1-like.
    
 
 0.735
skp1
S-phase kinase-associated protein 1; Belongs to the SKP1 family.
    
 
 0.638
hsd17b3
Testosterone 17-beta-dehydrogenase 3 isoform X1.
   
 0.630
Your Current Organism:
Ictalurus punctatus
NCBI taxonomy Id: 7998
Other names: I. punctatus, Silurus punctatus, channel catfish
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