Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
rbbp8DNA endonuclease RBBP8. (74 aa)    
Predicted Functional Partners:
mre11
Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.
   
 0.999
rad50
DNA repair protein RAD50 isoform X1.
    
 0.999
brca1
Breast cancer type 1 susceptibility protein isoform X2.
    
 0.999
bard1
BRCA1-associated RING domain protein 1.
    
 0.997
nbn
Nibrin.
    
 0.995
atm
Non-specific serine/threonine protein kinase.
    
 0.985
exo1
Exonuclease 1 isoform X1.
    
 0.984
sirt6
NAD-dependent protein deacetylase sirtuin-6 isoform X1.
    
 0.976
rb1
Retinoblastoma-associated protein.
    
   0.964
fancd2
Fanconi anemia group D2 protein isoform X2.
    
 
 0.963
Your Current Organism:
Ictalurus punctatus
NCBI taxonomy Id: 7998
Other names: I. punctatus, Silurus punctatus, channel catfish
Server load: low (34%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.