Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
dok1Docking protein 1. (588 aa)    
Predicted Functional Partners:
rasa1
Ras GTPase-activating protein 1.
    
 
 0.977
ret
Proto-oncogene tyrosine-protein kinase receptor Ret; Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands.
    
  0.947
inpp5d
Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 isoform X1.
    
 
 0.938
abl2
Tyrosine-protein kinase.
    
 0.851
abl1
Tyrosine-protein kinase.
    
 0.851
crkl
Crk-like protein.
    
 0.757
crk
Adapter molecule crk.
    
 0.757
CRK
Adapter molecule crk-like.
    
 0.757
LOC108265492
Docking protein 2-like.
   
 
 0.749
LOC108276246
Tyrosine-protein kinase.
    
 0.748
Your Current Organism:
Ictalurus punctatus
NCBI taxonomy Id: 7998
Other names: I. punctatus, Silurus punctatus, channel catfish
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