Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-expression
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[Homology]
Score
tlr2Toll-like receptor 2. (790 aa)    
Predicted Functional Partners:
myd88
Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.
   
 0.998
LOC108258270
Toll-like receptor 1.
  
  
0.974
tollip
Toll-interacting protein isoform X1.
    
 0.956
LOC108273830
Ras-related C3 botulinum toxin substrate 1-like.
   
 0.915
LOC108257150
Ras-related C3 Botulinum toxin substrate 1.
   
 0.915
LOC108272691
Toll-like receptor 2 type-2 isoform X1; Belongs to the Toll-like receptor family.
     
0.911
LOC108279945
Toll-like receptor 1; Belongs to the Toll-like receptor family.
     
0.909
il10
Interleukin-10.
   
 
 0.860
nod2
Nucleotide-binding oligomerization domain-containing protein 2.
   
 
 0.805
traf6
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
   
 0.750
Your Current Organism:
Ictalurus punctatus
NCBI taxonomy Id: 7998
Other names: I. punctatus, Silurus punctatus, channel catfish
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