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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
trip12E3 ubiquitin-protein ligase TRIP12. (2073 aa)    
Predicted Functional Partners:
ubr1
E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.
   
 0.987
ubr2
E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.
   
 0.987
ubr5
E3 ubiquitin-protein ligase UBR5 isoform X4.
   
  
0.987
uba3
NEDD8-activating enzyme E1 catalytic subunit isoform X1.
    
 0.982
LOC108272095
Ubiquitin-like modifier-activating enzyme 1; Belongs to the ubiquitin-activating E1 family.
   
 0.976
uba6
Ubiquitin-like modifier-activating enzyme 6 isoform X2.
   
 0.976
uba1
Ubiquitin-like modifier-activating enzyme 1; Belongs to the ubiquitin-activating E1 family.
   
 0.976
ltn1
E3 ubiquitin-protein ligase listerin.
   
 
 0.973
LOC108261162
Ubiquitin-conjugating enzyme E2 K-like; Belongs to the ubiquitin-conjugating enzyme family.
   
 0.963
ube2k
Ubiquitin-conjugating enzyme E2 K; Belongs to the ubiquitin-conjugating enzyme family.
   
 0.963
Your Current Organism:
Ictalurus punctatus
NCBI taxonomy Id: 7998
Other names: I. punctatus, Silurus punctatus, channel catfish
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