Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LOC108258328Suppressor of cytokine signaling 1-like. (202 aa)    
Predicted Functional Partners:
LOC108267827
Tyrosine-protein kinase receptor.
    
  0.913
eloc
Transcription elongation factor B polypeptide 1 isoform X1; Belongs to the SKP1 family.
    
 0.678
cul5
Cullin-5 isoform X1; Belongs to the cullin family.
   
 0.632
LOC108270091
Suppressor of cytokine signaling 4-like.
     
0.617
LOC108272001
Cytokine-inducible SH2-containing protein-like.
     
0.597
LOC108255976
Prostaglandin G/H synthase 1-like isoform X1.
   
  
 0.580
pik3r3
Phosphatidylinositol 3-kinase regulatory subunit alpha.
    
  0.579
pik3r1
Phosphatidylinositol 3-kinase regulatory subunit alpha.
    
  0.579
socs1
Suppressor of cytokine signaling 1.
  
  
0.570
LOC108254847
Cytokine-inducible SH2-containing protein-like.
     
0.547
Your Current Organism:
Ictalurus punctatus
NCBI taxonomy Id: 7998
Other names: I. punctatus, Silurus punctatus, channel catfish
Server load: low (16%) [HD]