adcy5 protein (Ictalurus punctatus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

adcy5

Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1193 aa)

Predicted Functional Partners:

LOC108262790

0.965

gnas

0.965

gnal

0.965

LOC108267323

0.952

prkacb

0.951

kapca

0.951

prkaca

0.951

LOC108263758

0.911

ntpcr

0.909

nudt2

0.900

Your Current Organism:

Ictalurus punctatus

NCBI taxonomy Id: 7998
Other names: I. punctatus, Silurus punctatus, channel catfish

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC108262790	LOC108263758	ENSIPUP00000000119	ENSIPUP00000011727	Guanine nucleotide-binding protein G(Olf) subunit alpha-like.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.856
LOC108262790	adcy5	ENSIPUP00000000119	ENSIPUP00000001977	Guanine nucleotide-binding protein G(Olf) subunit alpha-like.	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.965
LOC108262790	gnal	ENSIPUP00000000119	ENSIPUP00000026580	Guanine nucleotide-binding protein G(Olf) subunit alpha-like.	Guanine Nucleotide-binding protein G(olf) subunit alpha.	0.901
LOC108262790	gnas	ENSIPUP00000000119	ENSIPUP00000016220	Guanine nucleotide-binding protein G(Olf) subunit alpha-like.	Guanine nucleotide-binding protein G(S) subunit alpha.	0.901
LOC108263758	LOC108262790	ENSIPUP00000011727	ENSIPUP00000000119	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	Guanine nucleotide-binding protein G(Olf) subunit alpha-like.	0.856
LOC108263758	adcy5	ENSIPUP00000011727	ENSIPUP00000001977	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.911
LOC108263758	gnal	ENSIPUP00000011727	ENSIPUP00000026580	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	Guanine Nucleotide-binding protein G(olf) subunit alpha.	0.856
LOC108263758	gnas	ENSIPUP00000011727	ENSIPUP00000016220	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	Guanine nucleotide-binding protein G(S) subunit alpha.	0.856
LOC108267323	adcy5	ENSIPUP00000017531	ENSIPUP00000001977	cAMP-dependent protein kinase catalytic subunit beta isoform X2; Belongs to the protein kinase superfamily.	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.952
LOC108267323	kapca	ENSIPUP00000017531	ENSIPUP00000011233	cAMP-dependent protein kinase catalytic subunit beta isoform X2; Belongs to the protein kinase superfamily.	Camp-dependent protein kinase catalytic subunit alpha isoform X1; Belongs to the protein kinase superfamily.	0.900
LOC108267323	prkaca	ENSIPUP00000017531	ENSIPUP00000013646	cAMP-dependent protein kinase catalytic subunit beta isoform X2; Belongs to the protein kinase superfamily.	cAMP-dependent protein kinase catalytic subunit alpha; Belongs to the protein kinase superfamily.	0.900
LOC108267323	prkacb	ENSIPUP00000017531	ENSIPUP00000004823	cAMP-dependent protein kinase catalytic subunit beta isoform X2; Belongs to the protein kinase superfamily.	cAMP-dependent protein kinase catalytic subunit beta isoform X1; Belongs to the protein kinase superfamily.	0.900
adcy5	LOC108262790	ENSIPUP00000001977	ENSIPUP00000000119	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Guanine nucleotide-binding protein G(Olf) subunit alpha-like.	0.965
adcy5	LOC108263758	ENSIPUP00000001977	ENSIPUP00000011727	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.911
adcy5	LOC108267323	ENSIPUP00000001977	ENSIPUP00000017531	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	cAMP-dependent protein kinase catalytic subunit beta isoform X2; Belongs to the protein kinase superfamily.	0.952
adcy5	gnal	ENSIPUP00000001977	ENSIPUP00000026580	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Guanine Nucleotide-binding protein G(olf) subunit alpha.	0.965
adcy5	gnas	ENSIPUP00000001977	ENSIPUP00000016220	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Guanine nucleotide-binding protein G(S) subunit alpha.	0.965
adcy5	kapca	ENSIPUP00000001977	ENSIPUP00000011233	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Camp-dependent protein kinase catalytic subunit alpha isoform X1; Belongs to the protein kinase superfamily.	0.951
adcy5	ntpcr	ENSIPUP00000001977	ENSIPUP00000018686	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Cancer-related nucleoside-triphosphatase.	0.909
adcy5	nudt2	ENSIPUP00000001977	ENSIPUP00000016710	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Bis(5'-nucleosyl)-tetraphosphatase [asymmetrical].	0.900