Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
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Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
LOC108258689UPF0472 protein C16orf72 homolog. (259 aa)    
Predicted Functional Partners:
huwe1
E3 ubiquitin-protein ligase HUWE1 isoform X9.
    
 
 0.880
usp7
Ubiquitin carboxyl-terminal hydrolase 7 isoform X1; Belongs to the peptidase C19 family.
   
 
 0.759
pole3
DNA polymerase epsilon subunit 3.
    
 
 0.727
ipo4
Importin-4.
    
   0.725
phgdh
D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
    
   0.725
mars
methionine--tRNA ligase, cytoplasmic isoform X3.
    
   0.650
ENSIPUP00000036453
methionyl-tRNA synthetase 1.
    
   0.650
yars1
Tyrosine--tRNA ligase.
    
   0.626
rnaseh2c
Ribonuclease H2 subunit C.
    
 
 0.600
mcm7
DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]
    
   0.553
Your Current Organism:
Ictalurus punctatus
NCBI taxonomy Id: 7998
Other names: I. punctatus, Silurus punctatus, channel catfish
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